Antimicrobial and Phytochemical Studies on Extracts of Bucholzia coriacea Seeds

Research Paper (postgraduate) from the year 2013 in the subject Chemistry - Bio-chemistry, grade: none, Madonna University Elele, Nigeria, course: Pharmaceutical and Medicinal Chemistry, language: English, abstract: The in vitro antimicrobial activity of crude methanol and aqueous extracts of the seeds of Bucholzia coriacea were investigated. The extracts exhibited antimicrobial activities against Escherichia coli, klebsiella pneumonia, Bacillus subtilis, Staphylococcus aureus, Salmonella typhii, Bacillus cereus and Pseudomonas aeruginosa. The minimum inhibitory concentration (MIC) of the ethanol extract was between 0.50 - 6.00 mgml-1 while the minimum bactericidal concentration ranged from 2.0 - 10.0. The methanol and water extracts exhibited antifungal activity against Candida albicans and Aspergillus niger with zones of inhibition of 7.50 and 2.80mm for Candida albicans; and 6.0 and 2.0 for Aspergillus niger. Phytochemical screening revealed the presence of tannins, saponins, terpenoids, cardiac glycosides and alkaloids in the ethanolic and water extracts. The ability of the ethanol extract of Bucholzia coriacea seeds to inhibit the growth of bacteria and fungi is an indication of its broad spectrum antimicrobial potential which justifies its utilization in traditional medicine in treatment of infections.

Biography of Kingsley Adimabua: Kingsley Adimabua is a dedicated and experienced Humanitarian and Development worker hailing from Abuja, Nigeria. With a career spanning 11 years, Kingsley has made significant contributions to various esteemed organizations within the field. His passion for making a positive impact on communities and his expertise in Monitoring and Evaluation (M&E) and Information and Knowledge Management have set him apart as a strong candidate. Throughout his professional journey, Kingsley has had the privilege of working with reputable organizations such as Malaria Consortium, Christian Aid, Cuso International, Save the Children, Oxfam Novib, eHealth Africa, CBM International, and Palladium in Nigeria. His notable achievements include establishing a harmonized Post Distribution Monitoring system for a consortium of organizations involved in the Nigerian Joint Humanitarian Response and implementing effective Information and Knowledge management systems for Oxfam Novib's humanitarian response. Kingsley's skill set extends beyond M&E and Information and Knowledge Management. He possesses expertise in establishing quality standards and internal quality assurance mechanisms and is proficient in statistical analysis using tools such as Excel, STATA, SPSS, Epi-Info, and MicroStrategy. Additionally, his excellent writing and presentation skills have been honed through his professional experience. Passionate about helping people and driven by a desire to make a difference, Kingsley is a valuable asset to any team. He thrives on challenges, demonstrates adaptability, and possesses strong leadership qualities. Kingsley's unwavering dedication to humanitarian and development work, combined with his affinity for working with numbers and figures, make him a valuable addition to any organization. In his pursuit of professional growth, Kingsley is eager to take on increased responsibilities and contribute to an organization's growth in a higher role. He is patient, adaptable, and committed to exceeding expectations. Kingsley's ultimate goal is to continue making a positive impact on communities and contribute to the growth and success of the organization he joins. If given the opportunity, Kingsley would be delighted to discuss his qualifications further in an interview. For any inquiries or to schedule an interview, please feel free to contact him via email at greygoblings@gmail.com.