Aromatase Inhibitors
| Autor: | Barrington J. A. Furr |
|---|---|
| EAN: | 9783764386931 |
| eBook Format: | |
| Sprache: | Englisch |
| Produktart: | eBook |
| Veröffentlichungsdatum: | 28.03.2008 |
| Kategorie: | |
| Schlagworte: | Brustkrebs Drogen Treatment biosynthesis breast cancer cancer clinical trial development enzyme enzymes hormones hormone therapy pharmacology research tumor |
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This book provides the first comprehensive overview on the different aromatase inhibitors. Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not very potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency.
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