Cellular Senescence and Tumor Suppression
Autor: | Peter D. Adams, John M. Sedivy |
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EAN: | 9781441910752 |
eBook Format: | |
Sprache: | Englisch |
Produktart: | eBook |
Veröffentlichungsdatum: | 23.01.2010 |
Kategorie: | |
Schlagworte: | DNA Telomere aging biochemistry biology cancer cell chemistry development oncogene oncogenes proliferation senescence tissue tumor |
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As cells mature they naturally stop dividing and enter a period called senescence. But cellular senescence can also be induced prematurely by certain oncogenes involved in cancer development. Cellular senescence, a growth-arrest program that limits the lifespan of mammalian cells and prevents unlimited cell proliferation, is attracting considerable interest because of its links to tumor suppression.