Conditional Mutagenesis: An Approach to Disease Models
Autor: | Robert Feil, Daniel Metzger |
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EAN: | 9783540351092 |
eBook Format: | |
Sprache: | Englisch |
Produktart: | eBook |
Veröffentlichungsdatum: | 01.02.2007 |
Kategorie: | |
Schlagworte: | Chromosom conditional mutagenesis cre recombinase drug development gene knockout genes molecular mechanisms mouse models of human diseases pathophysiology physiology |
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In this book, leading experts provide timely and comprehensive information on methods for conditional mutagenesis in the mouse and their application to model human physiology and pathophysiology. The book illustrates how sophisticated genetic manipulations of the mouse genome are employed to model human diseases and to identify underlying molecular mechanisms. In addition, it considers the development of new drugs to treat human diseases.