Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System
| Autor: | Nicholas J. Brandon, Anthony R. West |
|---|---|
| EAN: | 9781118836323 |
| eBook Format: | PDF/ePUB |
| Sprache: | Englisch |
| Produktart: | eBook |
| Veröffentlichungsdatum: | 07.03.2014 |
| Untertitel: | From Biology to Drug Discovery |
| Kategorie: | |
| Schlagworte: | Alzheimer's Parkinson's central nervous system cyclic AMP cyclic GMP cyclic nucleotides drug discovery tools erectile dysfunction phosphodiesterases schizophrenia spinal cord injuries vitro assays |
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This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these, then focus on the areas of greatest scientific and medical interest to provide more detailed coverage. Therapeutic and drug discovery applications are covered for diseases including Alzheimer's, Parkinson's, schizophrenia, erectile dysfunction, and spinal cord injuries. There is also a chapter on drug discovery tools such as in vitro assays and X-ray structures for medicinal chemistry studies.
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