Drug Discovery for the Treatment of Addiction

With addiction a key target for drug discovery efforts, this book fills an important and timely need for medicinal chemists who need to understand complex neuroscience issues. The author illustrates medicinal chemistry's prominent role in treating addiction and covers specific drugs of abuse including narcotics, stimulants, depressants, nicotine, and marijuana.

• Interprets complex neuro- biological and pharmacological information, like the drug-reward system, for medicinal chemists
• Emphasizes neurotransmitters and neurochemical mechanisms of addictive drugs
• Pulls together information on the many potential drug targets for treating addiction
• Stresses unique medicinal chemistry problems when describing pharmacology testing methods and drug development

Brian S. Fulton is a Visiting Lecturer in the Department of Chemistry and Chemical Biology at Northeastern University and has taught courses in organic chemistry, spectroscopy, and pharmaceutical sciences and has taught a one-semester course, Medicinal Chemistry of Psychiatric Drugs, at Harvard University Extension School. From 1987 – 2005, Dr. Fulton worked as an industrial organic chemist in the US and Europe. He obtained his B.S. in Chemistry at Missouri State University and his Ph.D. in Organic Chemistry at Iowa State University. He has written 17 peer-reviewed publications and given 8 presentations at scientific meetings.