| EAN: | 9780128164341 |
|---|---|
| Sachgruppe: | Wirtschaft |
| Sprache: | Englisch |
| Seitenzahl: | 394 |
| Produktart: | Gebunden |
| Veröffentlichungsdatum: | 13.11.2019 |
| Untertitel: | Volume 7 |
| Schlagworte: | Business / Economics / Finance |
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"Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy, Volume Seven, describes the fundamental aspects of efflux pumps of the ATP-binding cassette superfamily in cancer resistance pathways, along with strategies to target and improve chemotherapy efficacy. Pumps of the ATP-binding cassette superfamily (ABCs) regulate the access of drugs to the intracellular space. In this context, the overexpression of ABCs is a well-known mechanism of multidrug resistance in cancer and is associated with therapeutic failure. Cancer types discussed include breast, endocrine, hematologic, gastrointestinal, musculoskeletal, lung, skin and central nervous system cancers."--