From Globular Proteins to Amyloids
| Autor: | Irena Roterman-Konieczna |
|---|---|
| EAN: | 9780081029824 |
| eBook Format: | |
| Sprache: | Englisch |
| Produktart: | eBook |
| Veröffentlichungsdatum: | 15.10.2019 |
| Kategorie: | |
| Schlagworte: | Amyloid Amyloidosis Anti-amyloid drugs Aá(1-42)Amyloid Chaperone Enzyme Enzyme-substrate interaction External force field Fibril Folding process Fuzzy oil drop model Globular protein Helical fragments Hydrophobic aá(1-42)Amyloid á-turn |
131,00 €*
Versandkostenfrei
Die Verfügbarkeit wird nach ihrer Bestellung bei uns geprüft.
Bücher sind in der Regel innerhalb von 1-2 Werktagen abholbereit.
From Globular Proteins to Amyloids proposes a model and mechanism for explaining protein misfolding. Concepts presented are based on a model originally intended to show how proteins attain their native conformations. This model is quantitative in nature and founded upon arguments derived from information theory. It facilitates prediction and simulation of the amyloid fibrillation process, also identifying the progressive changes that occur in native proteins that lead to the emergence of amyloid aggregations. - Introduces basic rules for protein folding, along with the conditions that result in misfolding - Presents research that lies in treating the aqueous environment as a continuum rather than a set of individual water molecules (i.e. the classic representation) - Provides practical applications for helping the prevention of amyloidosis and improving drug design
Weitere Produkte vom selben Autor