Genomics of Pattern Recognition Receptors
| Autor: | Anton G. Kutikhin, Arseniy E. Yuzhalin |
|---|---|
| EAN: | 9783034806886 |
| eBook Format: | |
| Sprache: | Englisch |
| Produktart: | eBook |
| Veröffentlichungsdatum: | 28.08.2013 |
| Untertitel: | Applications in Oncology and Cardiovascular Diseases |
| Kategorie: | |
| Schlagworte: | Cancer Cardiovascular diseases Immune response NOD-like receptors Pathogen-associated patterns Toll-like receptors |
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This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.
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