LC-MS in Drug Bioanalysis
Autor: | Q. Alan Xu, Timothy L. Madden |
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EAN: | 9781461438281 |
eBook Format: | |
Sprache: | Englisch |
Produktart: | eBook |
Veröffentlichungsdatum: | 15.07.2012 |
Kategorie: | |
Schlagworte: | Bioanalysis LC-MS LC-MS/MS Liquid chromatography MS anticancer drugs antidementia drugs antidepressants antiepileptic drugs antifundal drugs antimicrobial drugs antipsychotic drugs antiretroviral Drugs anxiolytic/hypnotic drugs cardiac |
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Clinical pharmacology plays an important role in today's medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography - mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in human biological matrixes for clinical pharmacology. Specifically, LC-MS is used to analyze: anticancer drugs antidementia drugs antidepressant drugs antiepileptic drugs antifundal drug antimicrobial drugs antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs cardiac drugs drugs for addiction immunosuppressant drugs mood stabilizer drugs This book will primarily cover the various methods of validation for LC-MS techniques and applications used in modern clinical pharmacology.