Mast Cells and Tumours
Autor: | Crivellato, Enrico Ribatti, Domenico |
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EAN: | 9789400794436 |
Sachgruppe: | Medizin |
Sprache: | Englisch |
Seitenzahl: | 152 |
Produktart: | Kartoniert / Broschiert |
Veröffentlichungsdatum: | 17.10.2014 |
Untertitel: | from Biology to Clinic |
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Mast cells have been implicated in various cell-mediated immune reactions, being found in tissues from multiple disease sites, and as a component of the host reaction to bacteria, parasite, and even virus infections. Mast cells have been shown to participate to angiogenic and tissue repair processes after injury. As most tumours contain inflammatory cell infiltrates, which often include plentiful mast cells, the question as to the possible contribution of these cells to tumour development has progressively been emerged. Mast cells may serve as a novel therapeutic target for cancer treatment. Includes supplementary material: sn.pub/extras