Mechanisms of Lymphocyte Activation and Immune Regulation XI
Autor: | Sudhir Gupta, Frederick W. Alt, Max D. Cooper, Fritz Melchers, Klaus Rajewsky |
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EAN: | 9780387465302 |
eBook Format: | |
Sprache: | Englisch |
Produktart: | eBook |
Veröffentlichungsdatum: | 21.05.2007 |
Untertitel: | B Cell Biology |
Kategorie: | |
Schlagworte: | autoimmunity biomedicine immunology lymphocyte protein |
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In recent years, major developments have increased understanding of various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires. These include the role of chromatin regulation and nuclear organization in understating the IgH gene regulation. These proceedings highlight recent developments in lymphocyte development, Ig gene rearrangements and somatic hypermutation, chromatin structure modification, B lymphocyte signaling and fate, receptor editing, and autoimmunity.