Metallothioneins in Normal and Cancer Cells
| Autor: | Piotr Dziegiel, Bartosz Pula, Christopher Kobierzycki, Mariusz Stasiolek, Marzenna Podhorska-Okolow |
|---|---|
| EAN: | 9783319274720 |
| eBook Format: | |
| Sprache: | Englisch |
| Produktart: | eBook |
| Veröffentlichungsdatum: | 04.02.2016 |
| Kategorie: | |
| Schlagworte: | cell senescence progression growth inhibitory factor intracellular zinc homeostasis neurodegeneration toxic metal detoxification |
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This book describes the structures of Metallothionein (MT) family members and the cellular functions of MT-1, MT-2 and MT-4 isoforms, as well as provides insights into divergent biological roles of MT-3. The authors explain the involvement of MT molecules in various processes related to carcinogenesis, including an organ-specific presentation of current data concerning their potential impact on the progression of various tumors and the regulatory role of MT family members in the function of the immune system.
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