MicroRNA in Regenerative Medicine
Autor: | Chandan K. Sen |
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EAN: | 9780124058583 |
eBook Format: | PDF/ePUB |
Sprache: | Englisch |
Produktart: | eBook |
Veröffentlichungsdatum: | 26.11.2014 |
Kategorie: | |
Schlagworte: | COPD CpG island DGCR8 DNA methylation Dicer EPCs HSC Hedgehog NF(B Notch PTEN REST/CoREST S6 STAT1 TGF1-Ç? TGFÇ? TLR4 TLX VEGF Wnt/Ç?-catenin adeno-associated virus (AAV) adenosine adipocyte adipogenes cis regulation Ç? cells |
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This work encapsulates the uses of miRNA across stem cells, developmental biology, tissue injury and tissue regeneration. In particular contributors provide focused coverage of methodologies, intervention and tissue engineering. Regulating virtually all biological processes, the genome's 1048 encoded microRNAs appear to hold considerable promise for the potential repair and regeneration of tissues and organs in future therapies. In this work, 50 experts address key topics of this fast-emerging field. Concisely summarizing and evaluating key findings emerging from fundamental research into translational application, they point to the current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA across repair and regeneration, and special coverage of methodologies and interventions as they point towards organ and tissue engineering - Multi-colour text layout with 150 colour figures to illustrate important findings - Take home messages encapsulate key lessons throughout text - Short chapters offer focused discussion and clear 'voice'