Microbe supported enhanced production of Rosmarinic acid of medicinal plants in vitro

Scientific Study from the year 2017 in the subject Biology - Micro- and Molecular Biology, , language: English, abstract: In the described study , the bio-enhancement of Rosmarinic acid( RA) was done successfully in suspension culture of Salvia officinalis and Ocimum sanctum suspended with E coli K12 entrapped alginate beads.It is reported that Tyrosin Amino transferase has a key role in the production of Rosmarinic acid , which is present in E coli K 12. Quantification by HPTLC indicated that the maximum RA content was noted in 4 weeks old (2050 mg/l) in Salvia officinalis suspension culture fed with Tyrosin 10 mg/100ml followed by 4 weeks old Ocimum sanctum suspension culture fed with Tyrosin 10 mg/100ml(715 mg/l), that are about 18 fold and 5 folds enhancement as compared to control. The method for significantly enhancement of RA was reported for the first time.

Dr Pratibha Chaturvedi is Ph D from Rajasthan University.She has vast Post Doctoral work experience of over 14years in the field of plant Biotechnology and Biochemistry. She has to her credit 4 books on Medicinal plants, more than 35 Research papers published in various research journals of national and international repute. Her work has been awarded by several reputed organizations. A women scientist awardee (Department of Science and Technology, Ministry of Science and Technology, New delhi) has main interest in Plant Biotechnology, Natural Products, Analytical plant Biochemistry, Proteomics, In vitro enhancement of Secondary metabolites, Plant Physiology, Virology and Animal cell culture etc. A life member of Indian Science congress, Dr Chaturvedi is recognized teacher of Mumbai University and Tibdewal University, Rajasthan for Ph D degree. She is also a member of editorial board in pubmed and other international journals.