Mitochondrial Dysfunction Caused by Drugs and Environmental Toxicants
| Autor: | Yvonne Will, James A. Dykens |
|---|---|
| EAN: | 9781119329732 |
| eBook Format: | |
| Sprache: | Englisch |
| Produktart: | eBook |
| Veröffentlichungsdatum: | 21.03.2018 |
| Kategorie: | |
| Schlagworte: | drug-mitochondria interactions drug safety drug transport and detoxification mitochondrial dysfunction mitochondrial medicine mitochondrial pharmacology mitochondrial toxicity |
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Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided.
• Covers both basic science and applied technology / methods
• Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects
• Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development
• Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria
• Covers both basic science and applied technology / methods
• Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects
• Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development
• Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria
Yvonne Will, PhD, is a Senior Director and the Head of Science and Technology Strategy, Drug Safety Research and Development at Pfizer, Connecticut, USA. In addition to the prior edition of this book, she co-edited Drug Discovery Toxicology: From Target Assessment to Translational Biomarkers(Wiley, 2016).
James A. Dykens, PhD, oversees EyeCyte Therapeutics, a start-up developing treatments for progressive blinding diseases via targeting mitochondrial dysfunction. He co-edited the first edition of this book.Verwandte Artikel
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