Molecular Analysis of B Lymphocyte Development and Activation
Autor: | Harinder Singh, Rudolf Grosschedl |
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EAN: | 9783540263630 |
eBook Format: | |
Sprache: | Englisch |
Produktart: | eBook |
Veröffentlichungsdatum: | 30.03.2006 |
Kategorie: | |
Schlagworte: | B cell receptor DNA-binding proteins biochemistry cell class switch recombination cytokine cytokine receptors gene genes immunoglobulin protein proteins transcriptional regulators |
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The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation.