Molecular Biology of B Cells
Autor: | Tasuku Honjo, Michael Reth, Andreas Radbruch, Frederick Alt, Alberto Martin |
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EAN: | 9780323958967 |
eBook Format: | |
Sprache: | Englisch |
Produktart: | eBook |
Veröffentlichungsdatum: | 11.01.2024 |
Kategorie: | |
Schlagworte: | Control of B cell development Evolution of B cell receptors Ig genes and their rearrangements Maintenance and memory of the B cell system Mechanism of B cell receptor signaling Mucos Regulation of class switching and somatic hypermutation by AID |
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Molecular Biology of B Cells, Third Edition is a comprehensive reference to how B cells are generated, selected, activated, and engaged in antibody production. These developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Third Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on B cell development and function, the use of therapeutic antibodies in cancer and infectious disease, therapeutic targeting of B cells for clinical application, new developments in lymphoma biology. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Third Edition is the definitive resource, vital for researchers across molecular biology, immunology, and genetics. - Provides new research on normal versus abnormal B cell development and function - Contains studies on therapeutic antibodies in cancer and infectious diseases - Covers research on therapeutically targeting B cells in inflammation or autoimmune diseases