Multiple Testing Procedures with Applications to Genomics
| Autor: | Sandrine Dudoit, Mark J. van der Laan |
|---|---|
| EAN: | 9780387493176 |
| eBook Format: | |
| Sprache: | Englisch |
| Produktart: | eBook |
| Veröffentlichungsdatum: | 18.12.2007 |
| Kategorie: | |
| Schlagworte: | Annotation Gene Ontology Master Patient Index Microarray Resampling SAS Single Nucleotide Polymorphism gene expression genes genome sequence analysis statistics |
160,49 €*
Versandkostenfrei
Die Verfügbarkeit wird nach ihrer Bestellung bei uns geprüft.
Bücher sind in der Regel innerhalb von 1-2 Werktagen abholbereit.
This book establishes the theoretical foundations of a general methodology for multiple hypothesis testing and discusses its software implementation in R and SAS. These are applied to a range of problems in biomedical and genomic research, including identification of differentially expressed and co-expressed genes in high-throughput gene expression experiments; tests of association between gene expression measures and biological annotation metadata; sequence analysis; and genetic mapping of complex traits using single nucleotide polymorphisms. The procedures are based on a test statistics joint null distribution and provide Type I error control in testing problems involving general data generating distributions, null hypotheses, and test statistics.
Verwandte Artikel