EAN: | 9783319588438 |
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Auflage: | 001 |
Sachgruppe: | Technik |
Sprache: | Englisch |
Seitenzahl: | 300 |
Produktart: | Gebunden |
Herausgeber: | Pivonka, Peter |
Veröffentlichungsdatum: | 03.07.2017 |
Schlagworte: | Mechanik Orthopädie |
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The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors. Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.