Mycobacterial Lipid Antigens against Tuberculosis
| Autor: | Wang, Jin |
|---|---|
| EAN: | 9783330062580 |
| Sachgruppe: | Chemie |
| Sprache: | Englisch |
| Seitenzahl: | 204 |
| Produktart: | Kartoniert / Broschiert |
| Veröffentlichungsdatum: | 24.03.2017 |
| Untertitel: | Chemical synthesis and T Cell Activation |
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Tuberculosis (TB), caused by bacteria named Mycobacterium tuberculosis, is the second biggest infectious disease after AIDS. The cell envelope of M.tuberculosis contains many unique lipids which play a key role in the pathogenicity. Some of the lipids have been identified as antigens, the phenolic glycolipids (PGLs), the lipoarabinomannan (LAM), and the phosphatidylinositolmannoside (PIMs). This book provides a comprehensive discussion about the PIMs epitopes identification, synthesis, and its immunological activity presented by the the CD1 molecules.
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