This book presents the latest exciting advances in understanding of the structure and function of myelin in the central and peripheral nervous systems under normal and pathological conditions. Readers will find state of the art information from the perspectives of both basic neuroscience and clinical neurology and neuropathology. Detailed attention is paid to the findings and implications of recent research on the myelin-forming glial cells such as oligodendrocytes and Schwann cells. The discussion of myelin pathology encompasses a wide range of diseases and conditions, including, for example, multiple sclerosis, Pelizaeus-Merzbacher disease, traumatic brain and spinal cord injuries, brain tumors of glial cell origin, Charcot-Marie-Tooth disease, immune-mediated neuropathy, and diabetic neuropathy. The authors comprise researchers at the cutting edge of biotechnology and experts in the diseases discussed. The clearly written text is supported by numerous high-quality light and electron microscopy, CT, and MR images.



Kazunori Sango, MD, PhD, Associate Director & Project Leader
Diabetic Neuropathy Project, Department of Sensory and Motor Systems
Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan

Junji Yamauchi, PhD, Associate Professor & Group Leader
Department of Pharmacology, National Research Institute for Child Health and 
Development, Tokyo, Japan

Toru Ogata, MD, PhD, Director
Department of Rehabilitation for the Movement Functions, National 
Rehabilitation Center for Persons with Disabilities, Center for Sport Science and 
Health Promotion, Tokorozawa, Japan

Keiichiro Susuki, MD, PhD, Assistant Professor
Department of Neuroscience, Cell Biology, and Physiology
Boonshoft School of Medicine, Wright State University, Dayton, Ohio, USA

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