Natural Products and their Bioactives in Antidiabetic Drug Discovery

Enables researchers to effectively understand and use bioactive compounds to target, prevent, and manage diabetes

Natural Products and Their Bioactives in Antidiabetic Drug Discovery provides readers with an overview of recent research in new drug discovery against diabetic complications based on bioactives from NPs, bridging the gap between the public research institutes and private companies working to find drugs to treat diabetes. To aid in reader comprehension, the text includes case studies and illustrated examples in relevant chapters.

Part one presents chapters on fundamental concepts of diabetes mellitus (DM) and recent drug discovery progress along with the various druggable targets and challenges. Part two covers bioactive compounds targeting Type-1 Diabetes. Part three focuses on Type-2 Diabetes. In Part four, the contributors address gestational DM prevention and management with natural compounds.

Written by a global team of experts in the field, Natural Products and their Bioactives in Antidiabetic Drug Discovery covers sample topics such as:

• Obesity risk factor in patients with T1DM and possible role of nutritional therapy in its management
• Use of natural non-insulin drugs as a novel approach to enhance therapeutic outcomes against T1DM
• Effectiveness of functional foods in intervening the diabetic complications and realistic results in clinical trials
• Implementation of nanotechnology in improving the bioavailability and reducing the threshold dose of bioactive compounds
• Various antidiabetic mechanisms of action of different polyphenols and immunomodulatory role of NPs bioactives relevance in T1DM therapy
• Effects of natural products on genetics of gestational diabetes

With comprehensive coverage of recent research in new drug discovery against diabetic complications based on bioactives from NPs, Natural Products and Their Bioactives in Antidiabetic Drug Discovery is an essential resource for researchers and professionals involved in drug discovery and development, health care, medicinal chemistry, phytochemistry, plant science, and toxicology.

Kanti Bhooshan Pandey, PhD, is a Senior Scientist and Assistant Professor in the Faculty of Biological Sciences, AcSIR; CSIR-Central Salt & Marine Chemicals Research Institute, Gujarat, India.

Maitree Suttajit, PhD, is Professor Emeritus previously at School of Medicine, Chiang Mai University and later at School of Medical Sciences, University of Phayao, Thailand.

Pinar Atukeren, PhD, is a senior Professor in Medical Biochemistry teaching in ?stanbul Üniversitesi-Cerrahpa?a, Cerrahpa?a Faculty of Medicine, Department of Medical Biochemistry, and also the Founding Dean of ?stanbul Üniversitesi-Cerrahpa?a, Faculty of Pharmacy, Turkey.