Nitric Oxide Donors

Nitric Oxide Donors: Biomedical Applications and Perspectives presents the current state of art, challenges and innovations in the design of therapeutics nitric oxide donors with great impact in several aspects of human physiology and pathophysiology. Although considerable innovative progress has been achieved using Nitric Oxide donors in biomedical applications, certain drawbacks still need to be overcome to successfully translate these research innovations into clinical applications. This book encompasses several topics on nitric oxide such as its sources and biological properties; its performance in the cardiovascular and neurologic systems, in the human skin and its application in the treatment of neglected diseases, neurodegenerative disorders, and cancer. Additionally, it covers its role in inflammation and immunity, penile erection function, photodynamic therapy, antimicrobial activities. It also discusses the future of nitric oxide donors in combination with other therapeutic drugs, in implantable sensors, and nitric oxide releasing hydrogels and medical devices for topical applications. The book is a valuable source for researchers on different areas of biomedical field who are interested in the improvements that these molecules can make in the treatment of several conditions. - Provides background information about biology and chemistry of nitric oxide - Discusses the state-of-the-art in the design of nitric oxide releasing nanomaterials for biomedical applications - Covers the usage of nitric oxide donors in the treatment of several conditions, such as cancer, human skin, cardiovascular system, and immunity - Discusses the future of nitric oxide donors and their FDA approval

Amedea B. Seabra holds a diploma degree in Chemistry from University of São Paulo (USP). She finished her Ph.D. at Chemistry Institute, State University of Campinas (UNICAMP) in 2006. Thereafter, she worked as a Research Fellow at UNICAMP (2006-2008), and she took postdoctoral studies at the Chemistry and Biochemistry Department, Concordia University in Montreal, Canada (2008-2010).She is associated professor at Federal University of ABC (UFABC). Her presentresearch is focused on the preparation, characterization and evaluation of the cytotoxicity of nitric oxide-releasing nanomaterials for biomedical and agricultural applications.