Predictive Approaches in Drug Discovery and Development
| Autor: | J. Andrew Williams, Richard Lalonde, Jeffrey R. Koup, David D. Christ, Sean Ekins |
|---|---|
| EAN: | 9781118230268 |
| eBook Format: | ePUB |
| Sprache: | Englisch |
| Produktart: | eBook |
| Veröffentlichungsdatum: | 14.02.2012 |
| Untertitel: | Biomarkers and In Vitro / In Vivo Correlations |
| Kategorie: | |
| Schlagworte: | IVIVC biomarkers biotech biotech research drug development in vivo in vitro correlations pharmaceutical industry pharmaceutical research |
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Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers. Case histories and lessons from successful and unsuccessful applications of biomarkers are included along with key chapters on GLP validation, safety biomarkers and proteomics biomarkers. Regulatory agency perspectives and initiatives both in the US and internationally are also discussed.
J. Andrew Williams, PHD, is Director of Translational Oncology at Pfizer Oncology.
Richard Lalonde, PharmD, is Vice President and Global Head of Clinical Pharmacology at Pfizer.
Jeffrey Koup, PharmD, is a consultant for PKPD modeling and the owner of Lakeside PKPD, LLC.
David D. Christ, PHD, is a consultant with SNC Partners LLC.
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