EAN: | 9783319497112 |
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Auflage: | 001 |
Sachgruppe: | Chemie |
Sprache: | Englisch |
Seitenzahl: | 224 |
Produktart: | Gebunden |
Herausgeber: | Falk, Heinz Gibbons, Simon Kinghorn, A. Douglas Kobayashi, Jun'Ichi |
Veröffentlichungsdatum: | 20.02.2017 |
Schlagworte: | Arznei - Arzneimittel Chemie / Medizin Medikament Organische Chemie Pharmaka Tablette computer-assistedstructureelucidation; spectrumperdiction; isomergeneration; methylxanthines; caffeine; Camelliasinensis; structuralelucidation; drugcessationtreatment |
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The first contribution reviews the occurrence of xanthine alkaloids in the plant kingdom and the elucidation of the caffeine biosynthesis pathway, providing details of the N-methyltransferases, belonging to the motif B' methyltransferase family which catalyze three steps in the four step pathway leading from xanthosine to caffeine. The second contribution in this book provides a background on the molecule and related compounds and update knowledge on the most recent advances in Iboga alkaloids. The third contribution presents a comprehensive analysis of frequently occurring errors with respect to 13C NMR spectroscopic data and proposes a straightforward protocol to eliminate a high percentage of the most obvious errors.