| EAN: | 9780128215951 |
|---|---|
| Sachgruppe: | Biologie |
| Sprache: | Englisch |
| Seitenzahl: | 472 |
| Produktart: | Kartoniert / Broschiert |
| Herausgeber: | Giangrande, Paloma H. Rossi, John J. de Franciscis, Vittorio |
| Veröffentlichungsdatum: | 13.04.2022 |
| Untertitel: | The Evolving Landscape of RNA Therapeutics |
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Provides a comprehensive overview of RNA therapeutic modalities, from bench-to-bedside, with an emphasis on the increasingly impactful areas of gene therapy, oligonucleotide therapeutics, gene editing and delivery. International leaders in the field examine RNA-based therapeutics tools that have been developed to-date to modulate cellular processes such as transcription, translation and protein function. Approved RNA-based therapies and lessons learned from failed therapies are discussed in-depth, as are evolving advances in RNA biochemical analysis, and similar advances that are enabling clinical application of RNA-based therapies. Later sections discuss delivery technologies, remaining hurdles in research and translation, the therapy development process from the lab to the clinic, and novel RNA-based therapies currently in development.