Synaptic Plasticity and the Mechanism of Alzheimer's Disease
| Autor: | Dennis J. Selkoe, Antoine Triller, Yves Christen |
|---|---|
| EAN: | 9783540763307 |
| eBook Format: | |
| Sprache: | Englisch |
| Produktart: | eBook |
| Veröffentlichungsdatum: | 08.01.2008 |
| Kategorie: | |
| Schlagworte: | Alzheimer Parkinson alzheimer's disease amyloid precursor protein attention deficit disorder (ADD) autism autism spectrum disorder brain cortex glutamate receptor memory postsynaptic density receptor receptor trafficking synapse loss |
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A biochemical hypothesis - that Alzheimer's disease (AD) is a progressive cerebral amyloidosis caused by the aggregation of the amyloid b-protein (Ab) - preceded and enabled the discovery of etiologies. This volume serves as a record focused on bringing together investigators at the forefront of elucidating the structure and function of hippocampal synapses with investigators focused on understanding how early assemblies of Ab may compromise some of these synapses.
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