Synthesis and Biological Evaluation of Cu, Ni, Mn and Zn Complexes
| Autor: | Bukhari, Iftikhar Hussain Ehsan, Tayyeba Ilyas, Sadia |
|---|---|
| EAN: | 9783659623639 |
| Sachgruppe: | Chemie |
| Sprache: | Englisch |
| Seitenzahl: | 60 |
| Produktart: | Kartoniert / Broschiert |
| Veröffentlichungsdatum: | 22.10.2014 |
| Untertitel: | Azithromycin |
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New Schiff base complexes of Copper, Nickel, Manganese and Zinc derived from Azithromycin with salicylaldehyde have been synthesized. Complexes was synthesized and physico-chemically characterized by solubility testing, melting point and FTIR. The synthesized metal complex was evaluated for antibacterial activity against the multidrug resistant pathogens, such as Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus and antifungal activity in opposition to Aspergillus niger and Aspergillus flavus. The metal complex showed the significant antibacterial and antifungal activity in comparison with free ligand.
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