Synthesis and biological evaluation of pyrano-pyrazoles
Autor: | Chauhan, Mamta Solanki, Nilesh |
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EAN: | 9786204982908 |
Sachgruppe: | Chemie |
Sprache: | Englisch |
Seitenzahl: | 76 |
Produktart: | Kartoniert / Broschiert |
Veröffentlichungsdatum: | 26.07.2022 |
Untertitel: | Organic Chemistry |
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This book contains twenty novel pyrano[2,3-c]pyrazoles (N 301-320) were synthesized. Synthesis of 6-amino-5-cyano-4-aryl-4H-pyrazolo[2,3-c]pyrans (N 301-320) were achieved by biginelli reaction have been synthesized by one pot multi-component reaction of hydrazine hydrate, ethylacetoacetate, malononitrile, substituted salicylaldehyde, and ammonium chloride in the presence of ethanol as a solvent and various catalyst. The products were characterized by FT-IR, 1H NMR, 13C NMR and mass spectral analyses. The newly synthesized compounds are subjected to antibacterial, anti-tubercular and antifungal screening. Authors expected this book to contribute to this trend and multi component reactions.