The Immune Synapse as a Novel Target for Therapy
Autor: | Luis Graca |
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EAN: | 9783764382964 |
eBook Format: | |
Sprache: | Englisch |
Produktart: | eBook |
Veröffentlichungsdatum: | 18.12.2007 |
Kategorie: | |
Schlagworte: | Activation Antigen Monoclonal Antibodies T cell antibody autoimmunity biochemistry cell clinical trial drug immunity lead regulation research vaccine |
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This volume gives an overview on the progress in immune synapse research, from basic science to clinical trials, and the major mechanisms involved. It discusses how interfering with T cell activation may lead to immune tolerance, immune modulation, and the recruitment of regulatory T cells; the role of monoclonal antibodies in tolerance induction; and mechanisms maintaining dominant tolerance.