The Networking of Chaperones by Co-chaperones
| Autor: | Gregory Blatch, Adrienne Lesley Edkins |
|---|---|
| EAN: | 9783319117317 |
| eBook Format: | |
| Sprache: | Englisch |
| Produktart: | eBook |
| Veröffentlichungsdatum: | 08.12.2014 |
| Untertitel: | Control of Cellular Protein Homeostasis |
| Kategorie: | |
| Schlagworte: | Cell Stress Cellular Networks Chaperones Co-chaperones Heat Shock Proteins Protein Folding |
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Co-chaperones are important mediators of the outcome of chaperone assisted protein homeostasis, which is a dynamic balance between the integrated processes of protein folding, degradation and translocation. The Networking of Chaperones by Co-chaperones describes how the function of the major molecular chaperones is regulated by a cohort of diverse non-client proteins, known as co-chaperones. The second edition includes the current status of the field and descriptions of a number of novel co-chaperones that have been recently identified. This new edition has a strong focus on the role of co-chaperones in human disease and as putative drug targets. The book will be a resource for both newcomers and established researchers in the field of cell stress and chaperones, as well as those interested in cross-cutting disciplines such as cellular networks and systems biology.
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