The Orexin/Hypocretin System
| Autor: | Seiji Nishino, Takeshi Sakurai |
|---|---|
| EAN: | 9781592599509 |
| eBook Format: | |
| Sprache: | Englisch |
| Produktart: | eBook |
| Veröffentlichungsdatum: | 22.11.2007 |
| Untertitel: | Physiology and Pathophysiology |
| Kategorie: | |
| Schlagworte: | Nervous System biological fluid clinical application neuroendocrinology neurons pathophysiology physiology tissue |
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This cutting-edge review of the orexin/hypocretin system sets the stage for advanced research on the pathological mechanisms underlying the loss of orexin/hypocretin neurons in humans, regulation of sleep and wakefulness by the orexin/hypocretin system, and the role of the orexin/hypocretin system in many other physiological processes, including feeding, autonomic regulation, and neuroendocrine regulation. Topics of interest include assessment of functions and the physiology of orexin/hypocretin, its pathophysiology in human narcolepsy-cataplexy, and possible treatments and pharmacology. The authors also introduce several experimental methods for orexin/hypocretin research, and, using multidisciplinary approaches, explain their uses and limitations.
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