Molecular Biology of B Cells
Autor: | Tasuku Honjo, Michael Reth, Andreas Radbruch, Frederick Alt |
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EAN: | 9780123984906 |
eBook Format: | PDF/ePUB |
Sprache: | Englisch |
Produktart: | eBook |
Veröffentlichungsdatum: | 09.10.2014 |
Kategorie: | |
Schlagworte: | 3D-structure AID AID cofactors AID mutations in N- and C-terminal regions APRIL Activation-induced cytidine deaminase Activation-induced cytidine deaminase (AID) Adaptor proteins Adhesion molecules Affinity maturation Antibody Antibody hum |
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Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production.ÿAll of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality.ÿ The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application.ÿ With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. - Covers signaling mechanisms regulating B cell differentiation - Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab - Contains studies on B cell tumors from various stages of B lymphocytes - Offers an integrated view of all aspects of B cells to produce a normal immune response